Understanding Immune Hubs to Improve Immunotherapy

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Our Research

Our lab studies the cellular interactions that shape immune responses in human tumors, focusing on how these responses are regulated. Using a combination of large-scale genomic analyses and tissue imaging approaches, we have identified hubs in tumor tissues where tumor cells come into close contact with immune cells. By characterizing the cells in these hubs, and the gene networks that are turned on in these cells, our lab aims to uncover novel ways to harness the immune system in the fight against cancer.

Our Partners

Our People

We are a brand new lab located at the Gladstone Institutes in sunny Mission Bay looking for passionate students and postdoctoral fellows to join us in our mission to decode the cellular interaction networks that shape immune responses in human tumors. We are excited to grow into a cross-disciplinary, collaborative and diverse lab that includes clinicians, immunologists, geneticists, cancer researchers, and computational biologists.

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Keep up-to-date with the latest research from the Pelka lab.

Recent Lab News

December 2024

As we enter the last month of 2024, we can't help but remember all that we've accomplished in previous months: publishing our work, submitting our grants, collaborating with several other labs, and, best of all, celebrating our big and small wins.

It's safe to say that our goal of ending this year on a good note was successfully accomplished (especially after attending the Gladstone Holiday Party this month). Happy Holidays to all - here's to achieving even more next year!

November 2024

While we spent loads of time on our projects this month, we also spent loads of time together! We all attended the CRISPR Cures for Cancer Symposium and cheered Karin on in her presentation, we attended two separate GIGI speaker seminars and trainee lunches, we attended our Pelka Lab Thanksgiving party that Han generously hosted, and we ended the month with a well-deserved Thanksgiving break! We were so thankful for November (pun intended)!

October 2024

Grant season has nearly ended (thank goodness)! As we're settling back into the fall quarter, we're resuming several meetings, presentations, and seminars, but most importantly, celebrating the holiday season starting with the annual Gladstone Halloween Party! Hoping to end this year the same way we ended October - on a productive and successful note 🤞