Understanding Immune Hubs to Improve Immunotherapy

Our Research

Our lab studies the cellular interactions that shape immune responses in human tumors, focusing on how these responses are regulated. Using a combination of large-scale genomic analyses and tissue imaging approaches, we have identified hubs in tumor tissues where tumor cells come into close contact with immune cells. By characterizing the cells in these hubs, and the gene networks that are turned on in these cells, our lab aims to uncover novel ways to harness the immune system in the fight against cancer.

Our Partners

Our People

We are a brand new lab located at the Gladstone Institutes in sunny Mission Bay looking for passionate students and postdoctoral fellows to join us in our mission to decode the cellular interaction networks that shape immune responses in human tumors. We are excited to grow into a cross-disciplinary, collaborative and diverse lab that includes clinicians, immunologists, geneticists, cancer researchers, and computational biologists.

News

Media highlights of Pelka Lab's research.
Cancer Immunologist Karin Pelka Joins Gladstone Institutes
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Researchers discover immune cell “hubs” hiding in tumors
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SU2C Peggy Prescott Early Career Scientist Award in Colorectal Cancer Research
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Stand Up to Cancer Awards $1.1 Million in Grants to Research Teams
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Faith Fight Finish Foundation Gala
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‘Goodness, I’m getting emotional’: How Cowboys QB Dak Prescott brought Jerry Jones to tears at gala
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Stand Up to Cancer Grants First Peggy Prescott Award in Colorectal Cancer Research
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Stay Updated

Keep up-to-date with the latest research from the Pelka lab.

Excited to announce the launch of our lab homepage! http://PelkaLab.org
Stay tuned for more ... information to be added soon...

Excited about our Genomic Immunology Institute symposium coming up Nov 3! Register to learn more ... about what we’ve been building and to hear about how we’re using genomic technologies to engineer immunotherapies and understand human immunity 👇 https://twitter.com/StacieDodgson/status/1447953706771681285

Please check out the twitter thread about our recent paper! Huge thanks again to everyone involved ... in this effort!!!

Recent Lab News

September 2021

Cancer Immunologist Karin Pelka Joins Gladstone Institutes

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August 2021

Researchers discover immune cell “hubs” hiding in tumors

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April 2021

Karin Pelka was awarded an NIH Pathway to Independence Award K99/R00, National Cancer Institute